Polynucleotides are the talking point of the aesthetic industry at the moment and with their rapid rise in popularity, it’s essential to grasp the essence of these restorative injectables.

Polynucleotides are known as the future of regenerative injectables hailed for their ability to rejuvenate and regenerate the skin, similarly to skin boosters. However, unlike skin boosters, injectable polynucleotides are renowned for their wound-healing and bio-stimulating properties. 

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Excellent at boosting fibroblast production and inducing deep tissue repair processes, polynucleotides enhance the skin’s quality whilst also aiding with other concerns.

Some other key usages of polynucleotides include:

  • Acne scarring
  • Skin conditions such as rosacea, melasma and hyperpigmentation
  • Atrophic scarring
  • Alopecia and androgenic hair loss
  • Deep lines and sunken wrinkles
  • Skin rehydration and rejuvenation
  • Elastosis
  • Facial ageing such as sagging and the formation of fine lines
  • Lumpy scars

Frequently Asked Questions

Polynucleotide injectables are a groundbreaking aesthetic treatment to help you achieve the youthful, radiant skin you desire. Whilst new to aesthetic medicine, they have been used for a number of years in other clinical applications such as osteoarthritis and wound healing. Consisting of filtered, ultra-purified, and sterilised DNA and RNA fragments derived from salmon, they have been scientifically proven to have remarkable regenerative properties. These fragments work at a cellular level, stimulating fibroblasts to stimulate collagen synthesis, improve skin elasticity, and promote tissue repair. They possess the ability to soothe inflammation and restore the balance of melanocyte activity (skin pigmentation), resulting in a more even and refreshed skin tone.

Prior to receiving a treatment with Tu Aesthetica, you will be required to have a face-to-face consultation with an aesthetic doctor. They will assess your medical history, discuss your wants and needs, and devise a personalised treatment plan. They will also make clear the risks and benefits of the treatments, give you the opportunity to ask any questions you have, and together you will decide if the treatment is right for you. You will also be required to have photographs taken for insurance purposes prior to any procedure.

Before undergoing Polynucleotide treatment your aesthetic doctor will assess your anatomy and clean the area to be treated with a sterilising solution. They may wish to mark the injection sites according to your individual anatomy and will inject at those specific locations on your face.

A second and possibly third identical treatment two to three weeks after the preceding treatment will need to be undertaken to see the full effect of Polynucleotides.

Once consent has been obtained and photographs taken, the procedure itself will take around 20 minutes.

The procedure generally involves a number of injections with very fine mesotherapy needles and blunt ended cannulae, and this usually causes only a small amount of discomfort.

The downtime following Polynucleotide treatment is minimal, and you should be able to return to your normal daily activities immediately after your procedure.  However, we recommend that you avoid physical strain and sports on the first day after the treatment, and don’t have a sauna or steamy bath for the first few days.  Avoiding the sun and UV light is also highly recommended for the first few days post-treatment.

A course of treatments consists of two or three sessions spaced 2-4 weeks apart and improvements can begin to be seen a couple of weeks after the first treatment, with improvements continuing for up to 12 weeks following the final treatment.

Visible improvements can last as much as a year, with a recommendation for a single dose top up treatment every 6-9 months in order to maintain results for an extended period. 

Ensuring your safety and delivering effective results is our top priority. Polynucleotides are considered one of the safest skin regeneration treatments available, backed by experts in the field. There is likely to be an element of redness, soreness and possibly bruising due to the injections, but any reactions to the polynucleotides themselves are rare.

Treatment with Polynucleotides and other injectable aesthetic treatments are still largely unregulated in the UK, allowing for wide variation in the qualifications and experience of practitioners and the standard of treatment provided to patients.

At Tu Aesthetica your safety is our number one priority, and therefore, with us you will only have your injections performed by a currently practising, GMC registered, UK-trained doctor. Our doctors engage in regular training to remain current, skilled, and professional in the treatments they provide. All of our Doctors work within the NHS and undergo regular appraisal and revalidation.

It is important that you feel comfortable with your doctor, not only in their ability and knowledge, but also on a personal level. We encourage all our patients to carefully research the practitioner offering them treatment, and only to make an informed decision on proceeding with treatment once they are comfortable with their experience, their qualifications, and their manner.

Polynucleotides are injected in accordance with the clinical assessment of your aesthetic doctor based on the degree of repair needed and the areas needing treatment. As such the treatment packages are priced based on the amount of Polynucleotides required, the amount of time and skill needed to inject those specific areas, and the number of treatment sessions.